Preparation, characterization, and evaluation (in-vitro, ex-vivo, and in-vivo) of naturosomal nanocarriers for enhanced delivery and therapeutic efficacy of hesperetin.

The present study intends to formulate, characterize and appraise the phospholipid-based nanovesicular system for enhanced delivery of Hesperetin (HT). The quality by design (QbD) approach was employed to prepare Hesperetin naturosomes (HTN) using the solvent evaporation technique and assessed for p...

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Main Authors: Shailendra Gurav, Poonam Usapkar, Nilambari Gurav, Sameer Nadaf, Muniappan Ayyanar, Rucheera Verekar, Ritesh Bhole, Chintha Venkataramaiah, Goutam Jena, Rupesh Chikhale
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0274916