Recombinant Newcastle disease virus rL-RVG enhances the apoptosis and inhibits the migration of A549 lung adenocarcinoma cells via regulating alpha 7 nicotinic acetylcholine receptors in vitro

Recombinant Newcastle disease virus rL-RVG enhances the apoptosis and inhibits the migration of A549 lung adenocarcinoma cells via regulating alpha 7 nicotinic acetylcholine receptors in vitro

Abstract Background The aim of this study were to investigate the possible pro-apoptotic mechanisms of the recombinant Newcastle disease virus (NDV) strain rL-RVG, which expresses the rabies virus glycoprotein, in A549 lung adenocarcinoma cells via the regulation of alpha 7 nicotinic acetylcholine r...

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Bibliographic Details
Main Authors: Yulan Yan, Chunxiang Su, Min Hang, Hua Huang, Yinghai Zhao, Xiaomei Shao, Xuefeng Bu
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Virology Journal
Subjects:
Recombinant Newcastle disease virus
Rabies virus glycoprotein
Lung adenocarcinoma
α7 nicotinic acetylcholine receptors
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s12985-017-0852-z

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http://link.springer.com/article/10.1186/s12985-017-0852-z

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