Maturation of the Human Immunoglobulin Heavy Chain Repertoire With Age
B cells play a central role in adaptive immune processes, mainly through the production of antibodies. The maturation of the B cell system with age is poorly studied. We extensively investigated age-related alterations of naïve and antigen-experienced immunoglobulin heavy chain (IgH) repertoires. Th...
Glavni autori: | , , , , , , , , , , |
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Format: | Članak |
Jezik: | English |
Izdano: |
Frontiers Media S.A.
2020-08-01
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Serija: | Frontiers in Immunology |
Teme: | |
Online pristup: | https://www.frontiersin.org/article/10.3389/fimmu.2020.01734/full |