Studies using HPLC-PDA in gabapentin N-derivatization reactions with 9-fluorenylmethyl chloroformate (FMOC-Cl)

FMOC-Cl is a derivatizing agent widely used both in N-protection reactions of α-amino acids as well as in quantification and detection of amino acids and related molecules using HPLC-PDA or fluorescence analysis. In this work we studied the reaction of FMOC-Cl with gabapentin. However, it was observ...

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Bibliographic Details
Main Authors: Emanoel Hottes, Carla Regina G. R. Santos, Heloisa J. M. de Souza, Marco Edilson F. Lima, Rosane N. Castro
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2021-07-01
Series:Química Nova
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422021000500543&tlng=en