Endotoxin-Free Stx2B-C-CPE Vaccine and Its Optimized Adjuvant Regimen for Preventing Food Poisoning

Endotoxin-Free Stx2B-C-CPE Vaccine and Its Optimized Adjuvant Regimen for Preventing Food Poisoning

Background: Clostridium perfringens and Shiga toxin (Stx)-producing Escherichia coli (STEC) are common causes of food poisoning. We previously demonstrated the efficacy of Stx2B-C-CPE, a fusion protein of the C-terminal region of C. perfringens enterotoxin (C-CPE) and Shiga toxin 2 B subunit (Stx2B)...

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Bibliographic Details
Main Authors: Koji Hosomi, Atsushi Shimoyama, Atsushi Hinenoya, Noritoshi Hatanaka, Takafumi Noguchi, Hirotaka Ebina, Yoko Tojima, Mari Furuta, Masuo Kondoh, Hiroshi Kiyono, Shinji Yamasaki, Koichi Fukase, Jun Kunisawa
Format: Article
Language:English
Published: IMR Press 2023-01-01
Series:Frontiers in Bioscience-Landmark
Subjects:
clostridium perfringens
stec
vaccine
adjuvant
lipid a
alcaligenes
endotoxin
Online Access:https://www.imrpress.com/journal/FBL/28/1/10.31083/j.fbl2801015

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https://www.imrpress.com/journal/FBL/28/1/10.31083/j.fbl2801015

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