The Interaction of the Senescent and Adjacent Breast Cancer Cells Promotes the Metastasis of Heterogeneous Breast Cancer Cells through Notch Signaling

The Interaction of the Senescent and Adjacent Breast Cancer Cells Promotes the Metastasis of Heterogeneous Breast Cancer Cells through Notch Signaling

Chemotherapy is one of the most common strategies for tumor treatment but often associated with post-therapy tumor recurrence. While chemotherapeutic drugs are known to induce tumor cell senescence, the roles and mechanisms of senescence in tumor recurrence remain unclear. In this study, we used dox...

Full description

Bibliographic Details
Main Authors: Na Zhang, Jiafei Ji, Dandan Zhou, Xuan Liu, Xinglin Zhang, Yingqi Liu, Weifang Xiang, Meida Wang, Lian Zhang, Guannan Wang, Baiqu Huang, Jun Lu, Yu Zhang
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
doxorubicin
co-culture system
breast cancer cells senescence
Notch signaling
EMT
Online Access:https://www.mdpi.com/1422-0067/22/2/849

Internet

https://www.mdpi.com/1422-0067/22/2/849

Similar Items