PTPN22 Silencing in Human Acute T-Cell Leukemia Cell Line (Jurkat Cell) and its Effect on the Expression of miR-181a and miR-181b

PTPN22 Silencing in Human Acute T-Cell Leukemia Cell Line (Jurkat Cell) and its Effect on the Expression of miR-181a and miR-181b

Purpose: T-cell acute lymphoblastic leukemia (T-ALL) is one of the most common malignancies associated with T-lymphocytes, accounting for 10 to 15 percent of ALL cases in children and 25 percent in adults. Innovative therapeutic approaches that overcome ineffective treatments on tumor cells may be a...

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Bibliographic Details
Main Authors: Elham Baghbani, Vahid Khaze, Sanam Sadreddini, Ahad Mokhtarzadeh, Behzad Mansoori, Ali Mohammadi, Vida Vatankhahan, Parisa Toosi, Behzad Baradaran
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2018-06-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
T-ALL
PTPN22
miR-181a
miR-181b
Online Access:http://apb.tbzmed.ac.ir/PDF/apb-8-277.pdf

Internet

http://apb.tbzmed.ac.ir/PDF/apb-8-277.pdf

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