RNF115/BCA2 deficiency alleviated acute liver injury in mice by promoting autophagy and inhibiting inflammatory response

Abstract The E3 ubiquitin ligase RING finger protein 115 (RNF115), also known as breast cancer-associated gene 2 (BCA2), has been linked with the growth of some cancers and immune regulation, which is negatively correlated with prognosis. Here, it is demonstrated that the RNF115 deletion can protect...

Full description

Bibliographic Details
Main Authors: Jinqiu Feng, Shufang Ye, Bao Hai, Yaxin Lou, Mengyuan Duan, Pengli Guo, Ping Lv, Wenping Lu, Yingyu Chen
Format: Article
Language:English
Published: Nature Publishing Group 2023-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06379-7