Tamoxifen Twists Again: On and Off-Targets in Macrophages and Infections

Tamoxifen Twists Again: On and Off-Targets in Macrophages and Infections

Beyond the wide use of tamoxifen in breast cancer chemotherapy due to its estrogen receptor antagonist activity, this drug is being assayed in repurposing strategies against a number of microbial infections. We conducted a literature search on the evidence related with tamoxifen activity in macropha...

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Bibliographic Details
Main Authors: Chiara Sfogliarini, Giovanna Pepe, Arianna Dolce, Sara Della Torre, Maria Candida Cesta, Marcello Allegretti, Massimo Locati, Elisabetta Vegeto
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Pharmacology
Subjects:
tamoxifen
SERMs
macrophages
infections
drug repurposing
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.879020/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.879020/full

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