Overexpression of Renin-B Induces Warburg-like Effects That Are Associated with Increased AKT/mTOR Signaling

Overexpression of Renin-B Induces Warburg-like Effects That Are Associated with Increased AKT/mTOR Signaling

The classical secretory renin-a is known to be involved in angiotensin generation, thereby regulating not only blood pressure, but also promoting oxidative stress as well as apoptotic and necrotic cell death. In contrast, another cytosolic renin isoform named renin-b has been described, exerting pro...

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Bibliographic Details
Main Authors: Janine Golchert, Doreen Staar, Jonathan Bennewitz, Miriam Hartmann, Nadin Hoffmann, Sabine Ameling, Uwe Völker, Jörg Peters, Heike Wanka
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cells
Subjects:
H9c2 cells
cytosolic renin
transcriptome analysis
Warburg effect
AKT/mTOR signaling
Online Access:https://www.mdpi.com/2073-4409/11/9/1459

Internet

https://www.mdpi.com/2073-4409/11/9/1459

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