SARS-CoV-2 modulates virus receptor expression in placenta and can induce trophoblast fusion, inflammation and endothelial permeability

SARS-CoV-2 modulates virus receptor expression in placenta and can induce trophoblast fusion, inflammation and endothelial permeability

SARS-CoV-2 is a devastating virus that induces a range of immunopathological mechanisms including cytokine storm, apoptosis, inflammation and complement and coagulation pathway hyperactivation. However, how the infection impacts pregnant mothers is still being worked out due to evidence of vertical...

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Bibliographic Details
Main Authors: Chiara Agostinis, Miriam Toffoli, Mariagiulia Spazzapan, Andrea Balduit, Gabriella Zito, Alessandro Mangogna, Luisa Zupin, Tiziana Salviato, Serena Maiocchi, Federico Romano, Sergio Crovella, Francesco Fontana, Luca Braga, Marco Confalonieri, Giuseppe Ricci, Uday Kishore, Roberta Bulla
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
ACE2
TMPRSS2
CD147
pregnancy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.957224/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.957224/full

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