Novel model of calcium and inositol 1,4,5-trisphosphate regulation of InsP3 receptor channel gating in native endoplasmic reticulum
The InsP3R Ca2+-release channel has biphasic dependence on cytoplasmic free Ca2+ concentration ([Ca2+]i). InsP3 activates gating primarily by reducing high [Ca2+]i inhibition. To determine whether relieving Ca2+ inhibition is sufficient for activation, we examined single-channels in low [Ca2+]i in t...
| Päätekijät: | , |
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| Aineistotyyppi: | Artikkeli |
| Kieli: | English |
| Julkaistu: |
BMC
2004-01-01
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| Sarja: | Biological Research |
| Aiheet: | |
| Linkit: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000400004 |