Multi-Atlas MRI-Based Striatum Segmentation for 123I-FP-CIT SPECT (DAT-SPECT) Compared With the Bolt Method and SPECT-Atlas-Based Segmentation Method Toward the Accurate Diagnosis of Parkinson's Disease/Syndrome

Multi-Atlas MRI-Based Striatum Segmentation for 123I-FP-CIT SPECT (DAT-SPECT) Compared With the Bolt Method and SPECT-Atlas-Based Segmentation Method Toward the Accurate Diagnosis of Parkinson's Disease/Syndrome

Aims: This study aimed to analyze the performance of multi-atlas MRI-based parcellation for 123I-FP-CIT SPECT (DAT-SPECT) in healthy volunteers. The proposed method was compared with the SPECT-atlas-based and Bolt methods. 18F-FE-PE2I-PET (DAT-PET) was used as a reference.Methods: Thirty healthy sub...

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Bibliographic Details
Main Authors: Koji Sohara, Tetsuro Sekine, Amane Tateno, Sunao Mizumura, Masaya Suda, Takeshi Sakayori, Yoshiro Okubo, Shin-ichiro Kumita
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Medicine
Subjects:
123I-FP-CIT
18F-FE-PE2I
positron emission tomography
semi-quantification
multi-atlas MRI based parcellation
Bolt method
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.662233/full

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https://www.frontiersin.org/articles/10.3389/fmed.2021.662233/full

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