A phase II study of preoperative chemoradiation with tegafur-uracil plus leucovorin for locally advanced rectal cancer with pharmacogenetic analysis

A phase II study of preoperative chemoradiation with tegafur-uracil plus leucovorin for locally advanced rectal cancer with pharmacogenetic analysis

Abstract Background This study aimed to evaluate the efficacy of a high dose of oral tegafur-uracil (400 mg/m2) plus leucovorin with preoperative chemoradiation of locally advanced rectal cancer and to explore the impact of polymorphisms of cytochrome P 2A6 (CYP2A6), uridine monophosphate synthetase...

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Detalhes bibliográficos
Principais autores: Sun Young Kim, Ji Yeon Baek, Jae Hwan Oh, Sung Chan Park, Dae Kyung Sohn, Min Ju Kim, Hee Jin Chang, Sun-Young Kong, Dae Yong Kim
Formato: Artigo
Idioma:English
Publicado em: BMC 2017-03-01
coleção:Radiation Oncology
Assuntos:
Rectal neoplasms
Chemoradiotherapy
Tegafur
Uridine monophosphate synthetase
Acesso em linha:http://link.springer.com/article/10.1186/s13014-017-0800-5

Internet

http://link.springer.com/article/10.1186/s13014-017-0800-5

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