Quantitative assessment of mitochondrial DNA copies from whole genome sequencing
<p>Abstract</p> <p>Background</p> <p>Mitochondrial dysfunction is associated with various aging diseases. The copy number of mtDNA in human cells may therefore be a potential biomarker for diagnostics of aging. Here we propose a new computational method for the accurate...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-12-01
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Series: | BMC Genomics |