Quantitative assessment of mitochondrial DNA copies from whole genome sequencing

Quantitative assessment of mitochondrial DNA copies from whole genome sequencing

<p>Abstract</p> <p>Background</p> <p>Mitochondrial dysfunction is associated with various aging diseases. The copy number of mtDNA in human cells may therefore be a potential biomarker for diagnostics of aging. Here we propose a new computational method for the accurate...

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Main Authors:	Chu Hsueh-Ting, Hsiao William WL, Tsao Theresa TH, Chang Ching-Mao, Liu Yen-Wenn, Fan Chen-Chieh, Lin Han, Chang Hen-Hong, Yeh Tze-Jung, Chen Jen-Chih, Huang Dun-Ming, Chen Chaur-Chin, Kao Cheng-Yan
Format:	Article
Language:	English
Published:	BMC 2012-12-01
Series:	BMC Genomics

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