Fibroblast growth factor 21 inhibits ferroptosis following spinal cord injury by regulating heme oxygenase-1

Fibroblast growth factor 21 inhibits ferroptosis following spinal cord injury by regulating heme oxygenase-1

Interfering with the ferroptosis pathway is a new strategy for the treatment of spinal cord injury. Fibroblast growth factor 21 can inhibit ferroptosis and promote neurofunctional recovery, while heme oxygenase-1 is a regulator of iron and reactive oxygen species homeostasis. The relationship betwee...

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Bibliographic Details
Main Authors: Qi Gu, Weiping Sha, Qun Huang, Jin Wang, Yi Zhu, Tianli Xu, Zhenhua Xu, Qiancheng Zhu, Jianfei Ge, Shoujin Tian, Xiaolong Lin
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Neural Regeneration Research
Subjects:
ferroptosis; fibroblast growth factor 21; functional recovery; heme oxygenase-1; lipid peroxidation; neuron; reactive oxygen species; spinal cord injury
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=7;spage=1568;epage=1574;aulast=Gu

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=7;spage=1568;epage=1574;aulast=Gu

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