Postsynaptic dorsal column pathway activation during spinal cord stimulation in patients with chronic pain

Spinal cord stimulation (SCS) treatment for chronic pain relies on the activation of primary sensory fibres ascending to the brain in the dorsal columns. While the efficacy of SCS has been demonstrated, the precise mechanism of action and nature of the fibres activated by stimulation remain largely...

Full description

Bibliographic Details
Main Authors: Gerrit Eduard Gmel, Rosana Santos Escapa, Teddy Edmond Benkohen, Dave Mugan, John Louis Parker, Stefano Palmisani
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1297814/full