Extracellular Vesicles and Cx43-Gap Junction Channels Are the Main Routes for Mitochondrial Transfer from Ultra-Purified Mesenchymal Stem Cells, RECs

Extracellular Vesicles and Cx43-Gap Junction Channels Are the Main Routes for Mitochondrial Transfer from Ultra-Purified Mesenchymal Stem Cells, RECs

Mitochondria are essential organelles for maintaining intracellular homeostasis. Their dysfunction can directly or indirectly affect cell functioning and is linked to multiple diseases. Donation of exogenous mitochondria is potentially a viable therapeutic strategy. For this, selecting appropriate d...

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Bibliographic Details
Main Authors: Jiahao Yang, Lu Liu, Yasuaki Oda, Keisuke Wada, Mako Ago, Shinichiro Matsuda, Miho Hattori, Tsukimi Goto, Shuichi Ishibashi, Yuki Kawashima-Sonoyama, Yumi Matsuzaki, Takeshi Taketani
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
rapidly expanding clones (RECs)
mesenchymal stem cells (MSCs)
extracellular vesicles (Evs)
Cx43-gap junction channels (Cx43-GJCs)
mitochondrial transfer
Online Access:https://www.mdpi.com/1422-0067/24/12/10294

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https://www.mdpi.com/1422-0067/24/12/10294

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