Heat Shock Protein 27 Injection Leads to Caspase Activation in the Visual Pathway and Retinal T-Cell Response

Heat Shock Protein 27 Injection Leads to Caspase Activation in the Visual Pathway and Retinal T-Cell Response

Heat shock protein 27 (HSP27) is one of the small molecular chaperones and is involved in many cell mechanisms. Besides the known protective and helpful functions of intracellular HSP27, very little is known about the mode of action of extracellular HSP27. In a previous study, we showed that intravi...

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Bibliographic Details
Main Authors: Pia Grotegut, Philipp Johannes Hoerdemann, Sabrina Reinehr, Nupur Gupta, H. Burkhard Dick, Stephanie C. Joachim
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
glaucoma
heat shock protein 27 (HSP27)
retinal ganglion cell degeneration
apoptosis
T-cells
microglia
Online Access:https://www.mdpi.com/1422-0067/22/2/513

Internet

https://www.mdpi.com/1422-0067/22/2/513

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