Inhibition of phosphodiesterase suppresses allergic lung inflammation by regulating MCP-1 in an OVA-induced asthma murine model with co-exposure to lipopolysaccharide

Objective Asthma is a chronic inflammatory disease that can lead to severe problems with the respiratory system. This study aimed to evaluate the suppression of allergic airway inflammation of an asthma murine model by 3-isobutyl-1-methylxanthine (IBMX), which is a non-specific cyclic nucleotide pho...

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Bibliographic Details
Main Authors: Chang Doo Lee, Won Seok Choi, Yong Geon Choi, Hyun Sik Kang, Wang Tae Lee, Hong Jo Kim, Ji-Yun Lee
Format: Article
Language:English
Published: SAGE Publishing 2020-02-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/0300060520903663