Selective amputation of the pharynx identifies a FoxA-dependent regeneration program in planaria

Planarian flatworms regenerate every organ after amputation. Adult pluripotent stem cells drive this ability, but how injury activates and directs stem cells into the appropriate lineages is unclear. Here we describe a single-organ regeneration assay in which ejection of the planarian pharynx is sel...

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Bibliographic Details
Main Authors: Carolyn E Adler, Chris W Seidel, Sean A McKinney, Alejandro Sánchez Alvarado
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/02238