Cycloolivil Isolated from <i>Nardostachys jatamansi</i> Inhibits TNF-α/IFN-γ-Induced Chemokine Production by Blocking NF-κB and JAK/STAT Activation in HaCaT Keratinocytes

Cycloolivil Isolated from <i>Nardostachys jatamansi</i> Inhibits TNF-α/IFN-γ-Induced Chemokine Production by Blocking NF-κB and JAK/STAT Activation in HaCaT Keratinocytes

<i>Nardostachys jatamansi</i> is widely used as a traditional medicine in Asian countries. Numerous recent studies have reported the biological activities of its secondary metabolites and extracts. In this study, a total of 14 components were isolated, including cycloolivil and 2-(3′-hyd...

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Bibliographic Details
Main Authors: Chi-Su Yoon, Hwan Lee, Zhiming Liu, Linsha Dong, Gyoyoung Lee, Nayeon Kim, Hyuncheol Oh, Dong-Sung Lee
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Nardostachys jatamansi</i>
anti-skin inflammation
keratinocytes
JAK/STAT
NF-κB
Online Access:https://www.mdpi.com/1422-0067/25/6/3342

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https://www.mdpi.com/1422-0067/25/6/3342

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