HIV latency reversing agents act through Tat post translational modifications

HIV latency reversing agents act through Tat post translational modifications

Abstract Background Different classes of latency reversing agents (LRAs) are being evaluated to measure their effects in reactivating HIV replication from latently infected cells. A limited number of studies have demonstrated additive effects of LRAs with the viral protein Tat in initiating transcri...

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Bibliographic Details
Main Authors: Georges Khoury, Talia M. Mota, Shuang Li, Carolin Tumpach, Michelle Y. Lee, Jonathan Jacobson, Leigh Harty, Jenny L. Anderson, Sharon R. Lewin, Damian F. J. Purcell
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Retrovirology
Subjects:
HIV latency
LRA
Tat
Post-translational modification
Splicing
Online Access:http://link.springer.com/article/10.1186/s12977-018-0421-6

Internet

http://link.springer.com/article/10.1186/s12977-018-0421-6

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