Osteoclast-derived apoptotic bodies couple bone resorption and formation in bone remodeling

Abstract Bone remodeling is precisely coordinated by bone resorption and formation. Apoptotic osteoclasts generate large amounts of apoptotic bodies (ABs) marking the end of the bone resorption phase, whereas the functions of osteoclast-derived ABs remain largely unknown. Here, we identified the mol...

Full description

Bibliographic Details
Main Authors: Qinyu Ma, Mengmeng Liang, Yutong Wu, Fei Luo, Zaisong Ma, Shiwu Dong, Jianzhong Xu, Ce Dou
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-020-00121-1