Ccn6 Is Required for Mitochondrial Integrity and Skeletal Muscle Function in Zebrafish

Ccn6 Is Required for Mitochondrial Integrity and Skeletal Muscle Function in Zebrafish

Mutations in the CCN6 (WISP3) gene are linked with a debilitating musculoskeletal disorder, termed progressive pseudorheumatoid dysplasia (PPRD). Yet, the functional significance of CCN6 in the musculoskeletal system remains unclear. Using zebrafish as a model organism, we demonstrated that zebrafis...

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Bibliographic Details
Main Authors: Archya Sengupta, Deepesh Kumar Padhan, Ananya Ganguly, Malini Sen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
CCN6
PPRD
muscle
mitochondria
respiratory complex
zebrafish
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.627409/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.627409/full

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