Head-to-head comparison between plasma p-tau217 and flortaucipir-PET in amyloid-positive patients with cognitive impairment

Head-to-head comparison between plasma p-tau217 and flortaucipir-PET in amyloid-positive patients with cognitive impairment

Abstract Background Plasma phosphorylated tau (p-tau) has emerged as a promising biomarker for Alzheimer’s disease (AD). Studies have reported strong associations between p-tau and tau-PET that are mainly driven by differences between amyloid-positive and amyloid-negative patients. However, the rela...

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Main Authors: Nidhi S. Mundada, Julio C. Rojas, Lawren Vandevrede, Elisabeth H. Thijssen, Leonardo Iaccarino, Obiora C. Okoye, Ranjani Shankar, David N. Soleimani-Meigooni, Argentina L. Lago, Bruce L. Miller, Charlotte E. Teunissen, Hillary Heuer, Howie J. Rosen, Jeffrey L. Dage, William J. Jagust, Gil D. Rabinovici, Adam L. Boxer, Renaud La Joie
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
MCI (mild cognitive impairment)
Tau-PET
MRI
Plasma biomarkers
Online Access:https://doi.org/10.1186/s13195-023-01302-w

Internet

https://doi.org/10.1186/s13195-023-01302-w

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