Bryostatin-1 Attenuates Ischemia-Elicited Neutrophil Transmigration and Ameliorates Graft Injury after Kidney Transplantation

Bryostatin-1 Attenuates Ischemia-Elicited Neutrophil Transmigration and Ameliorates Graft Injury after Kidney Transplantation

Ischemia reperfusion injury (IRI) is a form of sterile inflammation whose severity determines short- and long-term graft fates in kidney transplantation. Neutrophils are now recognized as a key cell type mediating early graft injury, which activates further innate immune responses and intensifies ac...

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Bibliographic Details
Main Authors: Felix Becker, Linus Kebschull, Constantin Rieger, Annika Mohr, Barbara Heitplatz, Veerle Van Marck, Uwe Hansen, Junaid Ansari, Stefan Reuter, Benjamin Strücker, Andreas Pascher, Jens G. Brockmann, Trevor Castor, J. Steve Alexander, Felicity N. E. Gavins
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
kidney transplant
ischemia reperfusion injury
Bryostatin-1
translational research
Online Access:https://www.mdpi.com/2073-4409/11/6/948

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https://www.mdpi.com/2073-4409/11/6/948

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