TNIK regulates actin cytoskeleton morphology via Rho/ROCK/LIMK1 pathway in lung adenocarcinoma A549 cells

Objective To investigate the molecular mechanism of TNIK regulating actin cytoskeleton morphology in lung adenocarcinoma A549 cells, and determine its effects on the proliferation and apoptosis of the cancer cells when combined with mitosis-targeted drug. Methods RNA sequencing data were profiled to...

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Bibliographic Details
Main Authors: SUN Xuehua, ZHANG Lian, ZHANG Chundong, CHEN Quan
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2023-04-01
Series:陆军军医大学学报
Subjects:
Online Access:http://aammt.tmmu.edu.cn/html/202210102.htm