Intracerebroventricular injection of RFRP-3 delays puberty onset and stimulates growth hormone secretion in female rats

Intracerebroventricular injection of RFRP-3 delays puberty onset and stimulates growth hormone secretion in female rats

Abstract Background Puberty onset is a complex, organized biological process with multilevel regulation, and its physiopathological mechanisms are yet to be elucidated. RFRP-3, the mammalian ortholog to gonadotropin-inhibitory hormone, is implicated in inhibiting the synthesis and release of gonadot...

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Bibliographic Details
Main Authors: Xinghui Han, Yuanyuan He, Gulan Zeng, Yonghong Wang, Wen Sun, Junchao Liu, Yanyan Sun, Jian Yu
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Reproductive Biology and Endocrinology
Subjects:
RFRP-3
Puberty onset
Kiss-1
GH
Online Access:http://link.springer.com/article/10.1186/s12958-017-0254-5

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http://link.springer.com/article/10.1186/s12958-017-0254-5

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