PEX5R/Trip8b-HCN2 channel regulating neuroinflammation involved in perioperative neurocognitive disorders

PEX5R/Trip8b-HCN2 channel regulating neuroinflammation involved in perioperative neurocognitive disorders

Abstract Background Clinical and animal studies demonstrated that neuroinflammation from anesthesia (sevoflurane) is the main contributor to cause perioperative neurocognitive disorders (PND). Recently, it was reported that microglia respond to hyperpolarization-activated cyclic nucleotide-gated (HC...

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Bibliographic Details
Main Authors: Feng Xu, Yafeng Wang, Linlin Han, Daling Deng, Yuanyuan Ding, LuLin Ma, Qingtong Zhang, Xiangdong Chen
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Cell & Bioscience
Subjects:
Microglia
Neuroinflammation
Sevoflurane
HCN2
Perioperative neurocognitive disorders
Online Access:https://doi.org/10.1186/s13578-022-00892-6

Internet

https://doi.org/10.1186/s13578-022-00892-6

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