Generation of two induced pluripotent stem cell lines from hereditary amyloidosis patients with polyneuropathy carrying heterozygous transthyretin (TTR) mutation

Generation of two induced pluripotent stem cell lines from hereditary amyloidosis patients with polyneuropathy carrying heterozygous transthyretin (TTR) mutation

Hereditary transthyretin amyloidosis with polyneuropathy (ATTR-PN) results from specific TTR gene mutations. In this study, we generated two induced pluripotent stem cell (iPSC) lines derived from ATTR-PN patients with heterozygous TTR gene mutations (Ala97Ser and Phe64Leu). These iPSC lines exhibit...

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Bibliographic Details
Main Authors: Juan Melesio, Bernardo Bonilauri, Audrey Li, Paul D. Pang, Ronglih Liao, Ronald M. Witteles, Joseph C. Wu, Karim Sallam
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Stem Cell Research
Subjects:
hiPSC
Stem cells
Pluripotency
TTR
Transthyretin
Polyneuropathy
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506123002519

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http://www.sciencedirect.com/science/article/pii/S1873506123002519

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