Thrombopoietin-independent generation of platelet-like particles from megakaryoblastic cells

Abstract The use of megakaryoblastic leukemia MEG-01 cells can help reveal the mechanisms of thrombopoiesis. However, conventional in vitro activation of platelet release from MEG-01 cells requires thrombopoietin, which is costly. Here, we aim to develop a more straightforward and affordable method....

Full description

Bibliographic Details
Main Authors: Nuntiporn Nunthanasup, Nutpakal Ketprasit, Egarit Noulsri, Attakorn Palasuwan, Valery Combes, Kasem Kulkeaw, Duangdao Palasuwan
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50111-6