Lipocalin-2 participates in sepsis-induced myocardial injury by mediating lipid accumulation and mitochondrial dysfunction

Lipocalin-2 participates in sepsis-induced myocardial injury by mediating lipid accumulation and mitochondrial dysfunction

BackgroundSepsis-induced cardiomyopathy (SIC) is one major cause of death for sepsis but lacks timely diagnosis and specific treatment due to unclear mechanisms. Lipocalin-2 (LCN-2) is a key regulator of lipid metabolism which has been recently proved closely related to sepsis, however, the relation...

Full description

Bibliographic Details
Main Authors: Weizhuo Liu, Xiaoyu Guo, Lei Jin, Ting Hong, Qianyun Zhang, Fan Su, Yi Shen, Saiqi Li, Bin He
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
lipocalin-2
sepsis
myocardial injury
lipid metabolism
mitochondrial dysfunction
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.1009726/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.1009726/full

Similar Items