The Paradoxical Effects of Serum Amyloid-P Component on Disseminated Candidiasis

The Paradoxical Effects of Serum Amyloid-P Component on Disseminated Candidiasis

Serum amyloid P component (SAP) may play an important role in human fungal diseases. SAP binds to functional amyloid on the fungal surface and masks fungi from host immune processes, skewing the macrophage population from the pro-inflammatory M1 to the quiescent M2 type. We assessed the role of SAP...

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Bibliographic Details
Main Authors: Stephen A. Klotz, Peter N. Lipke
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pathogens
Subjects:
serum amyloid-P component (SAP)
C-reactive protein (CRP)
miridesap
disseminated candidiasis
murine model of disseminated candidiasis
invasive fungi
Online Access:https://www.mdpi.com/2076-0817/11/11/1304

Internet

https://www.mdpi.com/2076-0817/11/11/1304

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