Aminoglycoside induced ototoxicity associated with mitochondrial DNA mutations

Despite the risk of permanent ototoxic effects, aminoglycosides remain commonly utilized antibiotics worldwide due to low cost and efficiency in treating severe infections. Over the last two decades, mitochondrial mutations have been shown to enhance the likelihood of ototoxic injury. In particular...

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Bibliographic Details
Main Authors: Joseph Foster II, Mustafa Tekin
Format: Article
Language:English
Published: SpringerOpen 2016-07-01
Series:Egyptian Journal of Medical Human Genetics
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1110863016300325