Syndecans as Cell Surface Receptors in Cancer Biology. A focus on their interaction with PDZ domain proteins.

Syndecans as Cell Surface Receptors in Cancer Biology. A focus on their interaction with PDZ domain proteins.

Syndecans are transmembrane receptors with ectodomains that are modified by glycosaminoglycan chains. The ectodomains can interact with a wide variety of molecules, including growth factors, cytokines, proteinases, adhesion receptors, and extracellular matrix components. The four syndecans in mammal...

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Bibliographic Details
Main Authors: Bill eCheng, Marine eMontmasson, Laurent eTerradot, Patricia eRousselle
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Pharmacology
Subjects:
Cytoskeleton
Extracellular Matrix
Phosphorylation
Cancer
Syndecan
PDZ domain
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00010/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00010/full

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