P4HA1: A single-gene surrogate of hypoxia signatures in oral squamous cell carcinoma patients

Background and purpose: Hypoxia gene expression signatures are of high prognostic value for head and neck cancer patients. Recently, the prognostic information of a multiple-gene hypoxia signature was found to be provided by the mRNA level of P4HA1 alone (Tawk et al., 2016). Therefore, we studied th...

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Bibliographic Details
Main Authors: Matthias Kappler, Johanna Kotrba, Tom Kaune, Matthias Bache, Swetlana Rot, Daniel Bethmann, Henri Wichmann, Antje Güttler, Udo Bilkenroth, Susanne Horter, Lisa Gallwitz, Jacqueline Kessler, Thomas Greither, Helge Taubert, Alexander W. Eckert, Dirk Vordermark
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Clinical and Translational Radiation Oncology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S240563081730023X