Liquid-liquid extraction combined with high performance liquid chromatography-diode array-ultra-violet for simultaneous determination of antineoplastic drugs in plasma

A liquid-liquid extraction (LLE) combined with high-performance liquid chromatography-diode array detection method for simultaneous analysis of four chemically and structurally different antineoplastic drugs (cyclophosphamide, doxorubicin, 5-fluorouracil and ifosfamide) was developed. The assay was...

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Bibliographic Details
Main Authors: Ananda Lima Sanson, Suéllen Cristina Rennó Silva, Matheus Coutinho Gonçalves Martins, Alexandre Giusti-Paiva, Patrícia Penido Maia, Isarita Martins
Format: Article
Language:English
Published: Universidade de São Paulo 2011-06-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000200017