Exploring the causal association between epigenetic clocks and menopause age: insights from a bidirectional Mendelian randomization study
BackgroundEvidence suggests a connection between DNA methylation (DNAm) aging and reproductive aging. However, the causal relationship between DNAm and age at menopause remains uncertain.MethodsEmploying established DNAm epigenetic clocks, such as DNAm Hannum age acceleration (Hannum), Intrinsic epi...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2024-08-01
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| Series: | Frontiers in Endocrinology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2024.1429514/full |