Peptide-based anti-PCSK9 vaccines - an approach for long-term LDLc management.

Low Density Lipoprotein (LDL) hypercholesterolemia, and its associated cardiovascular diseases, are some of the leading causes of death worldwide. The ability of proprotein convertase subtilisin/kexin 9 (PCSK9) to modulate circulating LDL cholesterol (LDLc) concentrations made it a very attractive t...

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Bibliographic Details
Main Authors: Gergana Galabova, Sylvia Brunner, Gabriele Winsauer, Claudia Juno, Bettina Wanko, Andreas Mairhofer, Petra Lührs, Achim Schneeberger, Arne von Bonin, Frank Mattner, Walter Schmidt, Guenther Staffler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4256444?pdf=render