Vaccines to Prevent Coccidioidomycosis: A Gene-Deletion Mutant of Coccidioides Posadasii as a Viable Candidate for Human Trials

Vaccines to Prevent Coccidioidomycosis: A Gene-Deletion Mutant of Coccidioides Posadasii as a Viable Candidate for Human Trials

Coccidioidomycosis is an endemic fungal infection that is reported in up to 20,000 persons per year and has an economic impact close to $1.5 billion. Natural infection virtually always confers protection from future exposure, and this suggests that a preventative vaccine strategy is likely to succee...

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Bibliographic Details
Main Authors: John N. Galgiani, Lisa F. Shubitz, Marc J. Orbach, M. Alejandra Mandel, Daniel A. Powell, Bruce S. Klein, Edward J. Robb, Mana Ohkura, Devin J. Seka, Thomas M. Tomasiak, Thomas P. Monath
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Journal of Fungi
Subjects:
coccidioidomycosis
live-attenuate vaccines
cellular immunity
canines
Online Access:https://www.mdpi.com/2309-608X/8/8/838

Internet

https://www.mdpi.com/2309-608X/8/8/838

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