MiR-20a-5p represses the multi-drug resistance of osteosarcoma by targeting the SDC2 gene

Abstract Background As one of the hallmarks of cancer, chemoresistance hinders curative cancer chemotherapy in osteosarcoma (OS). MicroRNAs (miRNAs) act as key regulators of gene expression in diverse biological processes including the multi-chemoresistance of cancers. Methods Based on the CCK8 expe...

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Bibliographic Details
Main Authors: Fangfang Zhao, Youguang Pu, Mingda Cui, Haiyan Wang, Shanbao Cai
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Cancer Cell International
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12935-017-0470-2