Leveraging adrenergic receptor blockade for enhanced nonalcoholic fatty liver disease treatment via a biomimetic nanoplatform

Leveraging adrenergic receptor blockade for enhanced nonalcoholic fatty liver disease treatment via a biomimetic nanoplatform

Abstract Nonalcoholic fatty liver disease (NAFLD) is characterized by excessive lipid accumulation, steatosis and fibrosis. Sympathetic nerves play a critical role in maintaining hepatic lipid homeostasis and regulating fibrotic progression through adrenergic receptors expressed by hepatocytes and h...

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Bibliographic Details
Main Authors: Bingyuan Fei, Yuewu Zhao, Jine Wang, Panyue Wen, Junjie Li, Masaru Tanaka, Zheng Wang, Shuo Li
Format: Article
Language:English
Published: BMC 2024-09-01
Series:Journal of Nanobiotechnology
Subjects:
Nonalcoholic fatty liver disease
Adrenoceptor blockade
Biomimetic nanoplatform
Hepatic stellate cells
Liver steatosis
Online Access:https://doi.org/10.1186/s12951-024-02864-z

Internet

https://doi.org/10.1186/s12951-024-02864-z

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