Development of Oncolytic Vectors Based on Human Adenovirus Type 6 for Cancer Treatment

Development of Oncolytic Vectors Based on Human Adenovirus Type 6 for Cancer Treatment

Human Adenovirus type 6 (HAdV-C6) is a promising candidate for the development of oncolytic vectors as it has low seroprevalence and the intrinsic ability to evade tissue macrophages. However, its further development as a therapeutic agent is hampered by the lack of convenient cloning methods. We ha...

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Bibliographic Details
Main Authors: Ivan D. Osipov, Valeriia A. Vasikhovskaia, Daria S. Zabelina, Sergei S. Kutseikin, Antonina A. Grazhdantseva, Galina V. Kochneva, Julia Davydova, Sergey V. Netesov, Margarita V. Romanenko
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Viruses
Subjects:
adenovirus type 6 (HAdV-C6
Ad6)
oncolytic virus
virotherapy
adenoviral genome modification
cloning
Online Access:https://www.mdpi.com/1999-4915/15/1/182

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https://www.mdpi.com/1999-4915/15/1/182

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