Discovery and characterization of naturally occurring chalcones as potent inhibitors of bile salt hydrolases
Bile salt hydrolases (BSHs) play crucial roles in the deconjugation of conjugated bile acids and therefore are key targets for modulating bile acid metabolism. This study aimed to identify efficacious BSH inhibitors from a natural compound library and to characterize their inhibitory mechanisms. The...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Compuscript Ltd
2022-05-01
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| Series: | Acta Materia Medica |
| Subjects: | |
| Online Access: | https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2022-0003 |