Meaningful local signalling in sinoatrial node identified by random matrix theory and PCA

The sinoatrial node (SAN) is the pacemaker of the heart. Recently calcium signals, believed to be crucially important in rhythm generation, have been imaged in intact SAN and shown to be heterogeneous in various regions of the SAN with a lot of analysis relying on visual inspection rather than mathe...

Full description

Bibliographic Details
Main Authors: Chloe F Norris, Anna V Maltsev
Format: Article
Language:English
Published: IOP Publishing 2023-01-01
Series:Journal of Physics: Complexity
Subjects:
Online Access:https://doi.org/10.1088/2632-072X/acadc8