A rapid and sensitive UPLC-MS/MS method for the determination of flibanserin in rat plasma: application to a pharmacokinetic study

A rapid and sensitive UPLC-MS/MS method for the determination of flibanserin in rat plasma: application to a pharmacokinetic study

Abstract Background In this work, we aim to develop and validate a fast, simple, and sensitive method for the quantitative determination of flibanserin and the exploration of its pharmacokinetics. Methods Ultra-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) was the method o...

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Bibliographic Details
Main Authors: Long He, Wenting You, Sa Wang, Tian Jiang, Caiming Chen
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Chemistry
Subjects:
Flibanserin
Rat plasma
UHPLC-MS/MS
Pharmacokinetics
Online Access:http://link.springer.com/article/10.1186/s13065-019-0620-9

Internet

http://link.springer.com/article/10.1186/s13065-019-0620-9

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