Cortical thinning over two years after first-episode psychosis depends on age of onset

Abstract First-episode psychosis (FEP) patients show structural brain abnormalities at the first episode. Whether the cortical changes that follow a FEP are progressive and whether age at onset modulates these changes remains unclear. This is a multicenter MRI study in a deeply phenotyped sample of...

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Bibliographic Details
Main Authors: Laura Pina-Camacho, Kenia Martinez, Covadonga M. Diaz-Caneja, Gisela Mezquida, Manuel J. Cuesta, Carmen Moreno, Silvia Amoretti, Ana González-Pinto, Celso Arango, Eduard Vieta, Josefina Castro-Fornieles, Antonio Lobo, David Fraguas, Miguel Bernardo, Joost Janssen, Mara Parellada, PEPs Group
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:npj Schizophrenia
Online Access:https://doi.org/10.1038/s41537-021-00196-7