Prediction of hot spots in protein–DNA binding interfaces based on discrete wavelet transform and wavelet packet transform

Prediction of hot spots in protein–DNA binding interfaces based on discrete wavelet transform and wavelet packet transform

Abstract Background Identification of hot spots in protein–DNA binding interfaces is extremely important for understanding the underlying mechanisms of protein–DNA interactions and drug design. Since experimental methods for identifying hot spots are time-consuming and expensive, and most of the exi...

Full description

Bibliographic Details
Main Authors: Yu Sun, Hongwei Wu, Zhengrong Xu, Zhenyu Yue, Ke Li
Format: Article
Language:English
Published: BMC 2023-04-01
Series:BMC Bioinformatics
Subjects:
Protein–DNA complexes
Hot spot
Synthetic minority over-sampling technique
Discrete wavelet transform
Wavelet packet transform
Light gradient boosting machine
Online Access:https://doi.org/10.1186/s12859-023-05263-7

Internet

https://doi.org/10.1186/s12859-023-05263-7

Similar Items